I have only recently come across this and feel it is a little gem deserving wider use. It is available on 14-28day free trial.
The difference on this software is that the lab test out 'hundreds' of most camera bodies and lenses, analyse their characteristics and 'reverse engineer' corresponding compensation algorithms. Especially good for widish angle lenses barrel distortion, which is corrected fully automatically once you have loaded the data for the lens.
I have tried it out against DPP, Aperture & Capture One for some piggish shots from the year I had a 350D and it wins easily, teasing the rather elusive colour from some of the poorer lit shots. I also tried it against Nikon Capture NX2 for some difficult shots from my D80, perhaps ones I originally edited using 1.2 or 1.3 and it stands up well and fully corrects the 18-135 kit lens.
The interface is a little frivolous, though 10 minutes in funereal Capture One quickly makes one appreciate that, but intuitive to use. I thought that the Aperture 5 point levels correction was the ultimate in basic light optimisation (not shadows, an additional module in both), but the DxO 'lighting' is magical in comparison.
I wouldn't let any of these progs touch my organisation, but again for the minimum storage need of the intermediate tif file, DxO can be set to return to folder of origin with your chosen suffix, whereas you have to fight Aperture very inch of the way.
None of these progs has faciities for editing selected areas of an image, so only a pre process before finishing (in NX2 for me)